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septilin price in india Alexander Fleming discovered penicillin in 1928, starting the age of modern antibiotics. But as early as 1947, or four years after penicillin use became common, we began to see bacteria developing a resistance to antibiotics. As we used more and more antibacterials and antibiotics, strains of bacteria evolved into Superbugs, which are resistant to treatments. Those Superbugs include CRE bacteria, Clostridum difficile and Methicillin-resistant Staphylococcus aureus (MRSA), commonly known as staph. MRSA cells can grow to a colony of more than 1 million cells in less than a day. At 2 million Americans suffer from antibiotic-resistant bacteria every year, and 23,000 die.